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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Histone hypo-acetylation of Sox9 mediates nicotine-induced weak cartilage repair by suppressing BMSC chondrogenic differentiation

Fig. 6

Effects of nicotine on interaction of NFATc2 and HDAC1 in BMSCs. Assay was performed after 24 h of in vitro culture. a Interaction of NFATc2 and HDAC1 under stimulus of nicotine with different concentrations. b Effects of MLA and Si-NFATc2 on the interaction of NFATc2 and HDAC1 induced by nicotine. IgG is a negative control. Input is a positive control. NFATc2 is the precipitated protein. HDAC1 is the protein of interest. BMSCs bone marrow mesenchymal stem cells, HDAC1 histone deacetylase1, MLA methyllycaconitine, NFATc2 nuclear factor of activated T cell 2

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