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Table 1 Experimental groups and abbreviations used in the study

From: DNA topoisomerase IIβ stimulates neurite outgrowth in neural differentiated human mesenchymal stem cells through regulation of Rho-GTPases (RhoA/Rock2 pathway) and Nurr1 expression

Abbreviations

Experimental groups

hMSC

Control (untreated) human mesenchymal stem cells (hMSCs)

hMSC_mN3

Neural differentiated hMSCs

hMSC_topo IIβ(−)

Topo IIβ transfected (silenced) hMSCs with siRNAs

hMSC_topo IIβ(+)

Topo IIβ transfected (overexpressing) hMSCs with pEGFP_topo IIβ

hMSC_topo IIβ(−)_mN3

Topo IIβ transfected (silenced) hMSCs with siRNAs induced to neural differentiation

hMSC_topo IIβ(+)_mN3

Topo IIβ transfected (overexpressing) hMSCs with pEGFP_topo IIβ induced to neural differentiation