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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Essential role of ATP6AP2 enrichment in caveolae/lipid raft microdomains for the induction of neuronal differentiation of stem cells

Fig. 7

Disruption of CLR-M by GW4869 (GW) induces accumulation of ATP6AP2 protein in subcellular compartments. hADSCs derived from healthy and ND subjects differentiated with or without GW (20 μM, pretreated D-2/0). Expression of neural markers (TUJ1 (a), O4 (b) and GFAP (c)), and subcellular distribution (of ATP6AP2 (d–f)/CAV (g–i)/FLOT (j–l) proteins in cellular, CLR-Ms and postnuclear supernatant (PNS)). §P < 0.01: GW+ vs GW−. CLR-M caveolae/lipid raft membrane microdomain, D day, FLOT flotillin, ND neurodegenerative disease

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Stem Cell Research & Therapy

ISSN: 1757-6512