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Table 2 MSC immunophenotypic analysis of PL-MSCs versus FBS-MSCs

From: Human platelet lysate in mesenchymal stromal cell expansion according to a GMP grade protocol: a cell factory experience

 

CD90

CD105

CD73

HLA-DR

CD45

CD14

CD19

CD34

FBS-MSCs

95.5 ± 1.6

96.8 ± 1.5

98.7 ± 1.1

2.9 ± 0.8

0.3 ± 0.1

1.3 ± 0.5

1.6 ± 0.5

0.6 ± 0.1

PL-MSCs

96.6 ± 0.6

93.2 ± 2.6

97.7 ± 1.5

1.5 ± 0.3

0.2 ± 0.1

1.2 ± 0.2

1.4 ± 0.1

0.5 ± 0.1

  1. Values expressed as mean percentage ± SD of positive cells for MSC antigen expression
  2. n = 12. Cells analyzed at the third passage for each experimental condition. No significant differences were observed (p > 0.05)
  3. FBS fetal bovine serum, MSC mesenchymal stromal/stem cell, PL platelet lysate