Fig. 1
From: Changes in phenotype and differentiation potential of human mesenchymal stem cells aging in vitro
Propagation of in-vitro aging MSCs. a Numbers of cell population doubling (NCPD) decreased by 69% and 41% from P3 to P8 in the DMEM and αMEM groups, respectively. b As a result of the reduced proliferative capability, MSC population doubling time (CPDT) increased over time in both groups. Numbers represent the mean values. n = 5–8; *p < 0.05, versus the corresponding P8-MSCs cultured under the same expansion condition. αMEM, minimum essential medium alpha; DMEM, Dulbecco’s modified Eagle’s medium