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Fig. 8 | Stem Cell Research & Therapy

Fig. 8

From: Intravenous injection of allogeneic umbilical cord-derived multipotent mesenchymal stromal cells reduces the infarct area and ameliorates cardiac function in a porcine model of acute myocardial infarction

Fig. 8

Intravenous injection of allogeneic UC-MSCs increased mRNA expression of angiogenesis biomarkers in the infarct area and peri-infarct area of the LV myocardium at week 8 after AMI. Vascular endothelial growth factor (VEGF) and platelet/endothelial cell adhesion molecule 1 (PECAM-1) mRNA expression in the infarct area (a, d), border area (b, e), and remote area (c, f) of three groups. Data are presented as the mean ± SD. Phosphate-buffered saline (PBS) group, n = 3; low-dose group, n = 4; and high-dose group, n = 4. *P < 0.05

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