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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Melatonin rescued interleukin 1β-impaired chondrogenesis of human mesenchymal stem cells

Fig. 4

IL-1β and MLT treatment affected chondrogenic and apoptotic marker expression at mRNA level. Expression of ACAN (a), SOX9 (b), COL10A1 (c), MMP9 (d), MMP13 (e), and ADAMTS4 (f) measured by qPCR and normalized to GAPDH. Relative expression level of each gene on different stages of differentiation representative of three independent experiments. aP < 0.05 versus control group; bP < 0.05 versus IL-1β group. IL-1β interleukin-1β, MLT melatonin

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