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Table 1 Experimental design of animal study

From: Bone marrow mesenchymal stem cells do not enhance intra-synovial tendon healing despite engraftment and homing to niches within the synovium

Group Time point Number of sheep Surgery BM aspiration MION-labelled MSCs Non-labelled MSCs Gross assessment MRI Flow cytometery Histological evaluation
Control (PBS) Treated (MSC) Total
1 1 day 0 2 2  
2 1–2 week 1 3 4    
3 4 weeks 6 6 12     
4 12 weeks 8 8 16     
5 24 weeks 8 8 16     
  1. BM bone marrow, MION magnetic iron-oxide nanoparticle, MRI magnetic resonance imaging, MSC mesenchymal stem cell, PBS phosphate buffered saline, dots indicate procedures performed for each group