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Table 1 Experimental design of animal study

From: Bone marrow mesenchymal stem cells do not enhance intra-synovial tendon healing despite engraftment and homing to niches within the synovium

Group

Time point

Number of sheep

Surgery

BM aspiration

MION-labelled MSCs

Non-labelled MSCs

Gross assessment

MRI

Flow cytometery

Histological evaluation

Control (PBS)

Treated (MSC)

Total

1

1 day

0

2

2

●

●

●

 

●

●

●

●

2

1–2 week

1

3

4

●

●

●

 

●

●

 

●

3

4 weeks

6

6

12

●

●

 

●

●

  

●

4

12 weeks

8

8

16

●

●

 

●

●

  

●

5

24 weeks

8

8

16

●

●

 

●

●

  

●

  1. BM bone marrow, MION magnetic iron-oxide nanoparticle, MRI magnetic resonance imaging, MSC mesenchymal stem cell, PBS phosphate buffered saline, dots indicate procedures performed for each group
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Stem Cell Research & Therapy

ISSN: 1757-6512