Fig. 6
The expression levels of stem cell pathway target genes at 20% and 1% O2 (n = 4). Detected genes included hypoxia inducible genes HIF1-α, HIF2-α, and ARNT, Notch pathway downstream genes HES1, HES3, HEY1, and HEY2, Wnt/β-catenin downstream genes AXIN2, MMP7, and TCF-1, and Hedgehog downstream genes GLI1, PTCH1, PTCH2, and SMO. *P < 0.05, **P < 0.01