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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: A pivotal role of BEX1 in liver progenitor cell expansion in mice

Fig. 1

Hepatic BEX1 expression is upregulated in response to CDE diet. a Heat map representation of significantly changed genes in liver tissues of 3-week chow and CDE diet-fed mice (n = 3). b Expression of Bex1 in liver tissues of 3-week chow and CDE diet-fed mice assessed by real-time PCR (mean ± SEM, n = 5, **P < 0.01, Mann–Whitney U test). c Immunoblotting analysis of BEX1 expression in liver lysates of 3-week chow and CDE diet-fed mice. d Mice fed chow or CDE diet for 3 weeks, livers excised and frozen sections prepared. Histologic specimens dual-stained for EpCAM (red) and BEX1 (green). IF staining examined by confocal microscopy. Scale bars, 75 μm. e Percentages of EpCAM+BEX1+ cells, EpCAM+BEX1 cells, EpCAMBEX1+ cells and EpCAMBEX1 cells in liver tissues of CDE diet-fed mice (n = 4). BEX1 brain-expressed X-linked 1, CDE choline-deficient, ethionine-supplemented, EpCAM epithelial cell adhesion molecule, PV portal vein

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