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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Epithelial disruption: a new paradigm enabling human airway stem cell transplantation

Fig. 2

Histological images of the anterior mouse nose 2 or 24 h after PDOC treatment only; the septum (NS) separates the treated (left) and untreated control (right, solid black arrowheads) nasal airways. Regions of epithelial cell loss (black arrows), the presence of cell debris (open arrows), and a loss of basal cells and basal lamina integrity (open arrowheads) are apparent. Scale bars = 0.2 mm. Panels b and c are an enlargement of a; e and f are an enlargement of d. Panels a, b, d, and e are all H&E-stained; c and f are cytokeratin 5–stained serial sections from (b) and (e), respectively. Abbreviations: H&E haemotoxylin and eosin, NS not significant, PDOC polidocanol

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