Skip to main content
Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Eph/Ephrin-mediated stimulation of human bone marrow mesenchymal stromal cells correlates with changes in cell adherence and increased cell death

Fig. 3

Effects of the blockade of Eph/Ephrin signaling on BM-MSC. BM-MSC cultures treated for 3 and 6 days with distinct soluble Eph/Ephrin-Fc fusion proteins that block Eph/Ephrin signaling. a A lower number of cells per well on day 6 under all conditions except after EphA3-Fc and EphA4-Fc treatment. b These decreased values correlate well with increased percentages of apoptotic MSC in treated cultures after 3 and 6 days. c However, no significant differences in the percentage of cycling cells at any time point are found. Data were obtained from five different donors. *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.005, versus respective control

Back to article page