Fig. 1

Analysis of whole exosome treatment on fibroblast viability and migration. a The absorbance level detected from the emitted luminescence from viable cells. Whole exosome (Exo)-treated fibroblasts had the highest viability, followed by acellular gelatinous Wharton’s jelly (AGWJ)-treated cells. Lysed exosomes and no treatment or control (Ctrl) medium-treated cells had the lowest viability. N = 3, *p < 0.05, **p < 0.01. b Crystal violet stained scratch assay showing fibroblast migration without any treatment, whole exosome-treated, and lysed exosome-treated cells at 0 h and 24 h. Cell migration was increased when the cells were treated with whole exosomes; however, lysed exosome-treated cells diminished cell migration after 24 h. c Quantification of the number of cells which have migrated into the scratch zone. Whole exosome-treated cells had a significantly increased migration compared with control medium-treated cells. N = 3; *p < 0.05