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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Autologous transplantation of adipose-derived stem cells improves functional recovery of skeletal muscle without direct participation in new myofiber formation

Fig. 5

Effect of adipose-derived stem cell (ADSC) transplantation on myogenesis and fibrosis in regenerating TA. a Comparative analysis of mRNA from crushed TAs treated with ADSC or collagen hydrogel only. RT-qPCR analysis showed the expression levels of the transcription factors paired box protein domain 7 (Pax7) and myogenic differentiation antigen (MyoD) and structural component myosin heavy chain (MyHC) over time. b Comparative level of mRNA measured by RT-qPCR of collagen type I (Coll1) and transforming growth factor β1 (TGFβ1). All results are normalized to GAPDH expression and plotted in relation to healthy TA expression level; n = 3–5 per group

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