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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Biphasic modulation of insulin signaling enables highly efficient hematopoietic differentiation from human pluripotent stem cells

Fig. 4

Global transcriptome analysis during HSPC differentiation. a Flow cytometry sorting strategy for day 8 H1 and iPSC-derived CD34+CD43 and CD34+CD43 populations. b Heat maps of global transcriptome for H1 and iPSC-derived CD34+CD43+ and CD34+CD43 populations. c Upregulated genes enriched in CD34+CD43 population. d Upregulated genes enriched in CD34+CD43+ cells. e Heat maps of lineage specific transcription factors, surface markers, WNT, NOTCH, RA signaling pathways genes and HOX genes in CD34+CD43+ and CD34+CD43 populations. GO Gene Ontology, iPSC induced pluripotent stem cell

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