Skip to main content

Table 3 Effect of cisplatin and its combination with bone-marrow derived mesenchymal stem cells (BM-MSCs) on testicular protein levels of tumor necrosis factor alpha (TNF-α) and mRNA expression of inducible nitric oxide synthase (iNOS). All results were expressed as mean ± SD

From: The role of mesenchymal stem cells in chemotherapy-induced gonadotoxicity

Group

Normal

Cisplatin

BM-MSCs

TNF-α pg/mg protein

30.9 ± 5.1

77.11* ± 10.1

46.21#* ± 6.3

iNOS relative expression

0.1 ± 0.003

0.62* ± 0.15

0.22# ± 0.05

  1. *Significant difference from the normal group at p < 0.05. #Significant difference from cisplatin group at p < 0.05
Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512