Fig. 6From: The march of pluripotent stem cells in cardiovascular regenerative medicineThe PiggyBac transposition system. The PiggyBac transposase has the ability to integrate into the genomic DNA of the host cell a DNA sequence provided that it is flanked by ITR sequences. The same PiggyBac transposase can in turn excise this inserted material, leaving the genomic DNA virally unchanged. ITR inverted terminal repeatBack to article page