Fig. 1From: Epigenetic modification of mesenchymal stromal cells enhances their suppressive effects on the Th17 responses of cells from rheumatoid arthritis patientsThe effects of epigenetic regulators on the immunoregulatory properties of hMSCs. We quantified the expression of interleukin (IL)-10 and indoleamine 2,3-dioxygenase (IDO) mRNA in hMSCs by a real-time PCR and b Western blotting after treatment with various combinations of 5-azacitidine (A), 5-aza-2′-deoxycytidine (D), trichostatin A (T), and valproic acid (V). The data are presented as the mean ± SD, and represent three independent experiments (n = 3). *P < 0.05, **P < 0.01, ***P < 0.001, versus untreated controlBack to article page