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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Histone demethylase JMJD6 regulates cellular migration and proliferation in adipose-derived mesenchymal stem cells

Fig. 2

JMJD6 depletion promotes the wound-healing ability of ADSCs. a The shRNA mediated knockdown of JMJD6 in ADSCs. The JMJD6 mRNA expression level was determined by qRT-PCR. b ADSCs were infected with the viruses and selected with puromycin for 1 week. Next, the JMJD6 protein expression levels were examined by western blot experiments. c and d Wound-healing assay for JMJD6 knockdown ADSCs compared with ADSCs transfected with the scrambled (Scr) sequence. The graph presents the ratios of wound recovery of JMJD6 knockdown ADSCs relative to the control group. n = 3/group, Error bars represent the SD. **p < 0.01; *p < 0.05versus the control. Scale bar = 200 μm, magnification = ×100. ADSCs: adipose-derived mesenchymal stem cells, JMJD6 Jumonji C domain-containing protein 6

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