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Table 3 The top 10 significantly upregulated genes in polycystic ovary syndrome patient-derived induced pluripotent stem cells
| Gene name | Gene number | Gene Ontology molecular function term | Fold-change |
|---|---|---|---|
| IFI16 | NM_001206567 | Transcription, cell proliferation, hemopoiesis | 1484 |
| CAPN6 | NM_014289 | Calcium-dependent cysteine-type endopeptidase | 221.7 |
| LAMA4 | NM_001105206 | Extracellular matrix structural constituent | 151.6 |
| IL18 | NM_001562 | MAPK cascade, inflammatory and immune response | 96.9 |
| FOLH1B | NM_153696 | Metallopeptidase and dipeptidase activity, proteolysis | 80.2 |
| FOLH1 | NM_004476 | Folic acid-containing compound metabolic process | 78.2 |
| TBX5 | NM_080718 | Transcription factor activity, heart development | 76.4 |
| FBP1 | NM_000507 | AMP binding, fructose and glucose metabolic process | 69.2 |
| AGL | NM_000028 | Glycogen debranching enzyme, glucose metabolism | 42.7 |
| KIAA1324 | NM_020775 | Macroautophagy, regulation of apoptosis, trans-Golgi | 29.6 |
