Skip to main content

Table 1 Time course of urinary protein excretion in control and ADR rats receiving saline, bmMSCs, ucMSCs, kPSCs or CM-ucMSCs

From: Therapeutic potential of stromal cells of non-renal or renal origin in experimental chronic kidney disease

  Proteinuria (mg/day)
  0 days 7 days 14 days 21 days 28 days
Control 6 ± 1.1 10 ± 1.3 12 ± 1.2 13 ± 1.3 13 ± 1.7
ADR + saline 7 ± 0.6 71 ± 7* 344 ± 29* 528 ± 26* 501 ± 53*
ADR + bmMSCs 7 ± 0.7 59 ± 12* 270 ± 19* 411 ± 17* 526 ± 36*
ADR + ucMSCs 7 ± 0.6 71 ± 11* 345 ± 16* 476 ± 15* 512 ± 43*
ADR + kPSCs 7 ± 0.4 63 ± 11* 355 ± 28* 471 ± 52* 486 ± 38*
ADR + CM-ucMSCs 8 ± 0.6 73 ± 13* 366 ± 40* 527 ± 37* 454 ± 48*
  1. Data presented as mean ± standard error
  2. ADR adriamycin, bmMSC bone marrow mesenchymal stromal cell, ucMSC umbilical cord mesenchymal stromal cell, kPSC kidney perivascular stromal cell, CM-ucMSC conditioned medium obtained from umbilical cord mesenchymal stromal cell
  3. *p < 0.001 vs control at the corresponding time. Analysis of variance corrected with Tukey coefficient