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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: PARP1 inhibitor (PJ34) improves the function of aging-induced endothelial progenitor cells by preserving intracellular NAD+ levels and increasing SIRT1 activity

Fig. 4

Protein expression changes in senescent EPCs with PJ34 treatment. ac Poly (ADP-ribose) polymerase 1 (PARP1), poly ADP-ribose (PAR), sirtuin 1 (SIRT1), acetylated (ac)-p53, p53, and p21 were detected by Western blot after 24 h of treatment. *P < 0.05, **P < 0.01, ***P < 0.001, versus the control; #P < 0.05, ##P < 0.01, ###P < 0.001, versus H2O2 treatment

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