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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: PARP1 inhibitor (PJ34) improves the function of aging-induced endothelial progenitor cells by preserving intracellular NAD+ levels and increasing SIRT1 activity

Fig. 6

Effects of PJ34 on the protein levels of senescent EPCs after silencing sirtuin 1 (SIRT1). ac Poly (ADP-ribose) polymerase 1 (PARP1), poly ADP-ribose (PAR), SIRT1, acetylated (ac)-p53, p53, and p21 were detected by Western blot. *P < 0.05, **P < 0.01, ***P < 0.001, versus the control; #P < 0.05, ##P < 0.01, ###P < 0.001, versus H2O2 treatment. NS not significant

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