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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Inhibition of mTORC1 signaling protects kidney from irradiation-induced toxicity via accelerating recovery of renal stem-like cells

Fig. 1

Irradiation-induced renal toxicity in mice. C57BL/6 J mice exposed to 8.0 Gy of total body irradiation (TBI). Kidney tissues harvested at days 1, 3 and 7 (d1, d3, d7) post exposure. a Representative pictures by HE staining. Arrows represent damaged corpuscles. b Acute tubular necrosis (ANT) score in nonirradiated and irradiated kidneys. c Immunostaining of CD133 in nonirradiated and irradiated kidneys. Arrows represent CD133-positive staining. d Integrated optical density (IOD) of CD133 staining presented via imaging analysis. Nonirradiated renal tissues (CTL) used as controls. Bar = 50 μm. **p < 0.01 vs CTL; ***p < 0.001 vs CTL

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