Fig. 1
B-MSCs from IPF patients show increased senescence. a Proliferation rates of idiopathic pulmonary fibrosis (IPF) B-MSC (filled circles) compared with age-matched controls (Old; open circles), showing slower proliferation rates in IPF B-MSCs compared with age-matched controls. b Representative photos of B-MSCs subjected to Senescence-associated β-galactosidase (SA-β-gal) staining. c Percentage of SA-β-gal-positive cells from IPF patients and age-matched controls (Old); mean ± SEM; n = 3. d Expression of senescence markers p21, p16INK4A, and p53 measured by qRT-PCR; fold change (FC) ± SEM; *p < 0.05