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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Senescence of bone marrow-derived mesenchymal stem cells from patients with idiopathic pulmonary fibrosis

Fig. 5

Mitochondria in B-MSCs from IPF patients are more abundant but smaller compared with aged-matched controls. a Transmission electron microscopy (TEM; n = 2 and 4 per group) of B-MSCs from donor control (Old) and idiopathic pulmonary fibrosis (IPF) patients. Scale bars = 500 nm. b,c Quantitative analysis of morphometric data from TEM images (area and length). d Mitochondrial mass determined by MitoTracker Green (MTG) and normalized to cell number using DAPI; *p ≤ 0.05, **p ≤ 0.01

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