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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Decellularized human ovarian scaffold based on a sodium lauryl ester sulfate (SLES)-treated protocol, as a natural three-dimensional scaffold for construction of bioengineered ovaries

Fig. 7

Immunohistochemical assessments of POCs-DS (A-C) transplanted grafts. a Inhibin-α immunostaining for the detection of the granulosa cells. These cells (in brown) were scattered throughout the graft and some of them were organized into a follicle-like pattern (inset, a); Scale bars: 50 μm. b ER-positive brown cells were observed within the POCs-DS grafts. Strong staining intensity was observed in the cells located peripherally on the scaffolds (black arrows) compared with those located more centrally (inset, b); scale bars: 50 μm. c PR-positive cells were observed within the POCs-DS grafts as well; scale bar: 100 μm. (inset, c): PR-positive cells around an oocyte; scale bars: 50 μm. ER estrogen receptor, POCs-DS primary ovarian cells-seeded decellularized scaffolds, PR progesterone receptor

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Stem Cell Research & Therapy

ISSN: 1757-6512