Table 7 Anorectal function parameters before and after SMDC implantation (all patients)
From: Skeletal muscle-derived cell implantation for the treatment of sphincter-related faecal incontinence
| Â | Mean (SD) | Mean (95% CI) | |
|---|---|---|---|
V-2 | V4 | V4 – V-2 | |
Anal canal length (mm) | 15.9 (6.37) | 27.1 (9.47) | 11.1 (7.4; 14.8)* |
Anal sphincter rest pressure (mmHg) | 66.2 (35.00) | 72.5 (30.20) | 7.0 (−4.63; 18.66) |
Anal sphincter maximum squeeze pressure (mmHg) | 121.4 (56.82) | 130.7 (64.27) | 8.9 (−4.09; 21.87) |
Threshold volumes for first sensation (ml) | 30.5 (24.49) | 46.6 (22.09) | 16.5 (5.1; 27.9)* |
Threshold volumes for desire to defecate (ml) | 105.0 (61.59) | 100.3 (40.69) | 1.5 (−20.7; 23.6) |
Threshold volumes for urgency to defecate (ml) | 111.8 (65.09) | 100.3 (40.69) | −3.2 (− 25.9; 19.4) |
Maximum tolerable volume (ml) | 165.1 (72.98) | 164.5 (55.64) | 2.9 (−19.5; 25.3) |