Improving hematopoietic recovery through modeling and modulation of the mesenchymal stromal cell secretome

Table 1 Proteins expressed by MSCs and significantly correlated with mouse survival, post-irradiation

Pearson linear regression	Partial least squares regression	Overlapping proteins
ANG-1	IL-6	IL-6
BMP2	IL-8	IL-8
EGF	BMP2	BMP2
FGF1	EGF	EGF
IL-15	FGF1	FGF1
IL-6	MCP-1	RANTES
IL-8	RANTES	VEGF-A
RANTES	VEGF-A	ANG-1
THPO	ANG-1
VEGF-A

Overlapping proteins indicate those proteins identified as correlated significantly by both Pearson linear regression and partial least squares regression
ANG-1 angiopoietin-1, BMP-2 bone morphogenetic protein 2, EGF epidermal growth factor, FGF-1 fibroblast growth factor 1, IL-6 interleukin 6, IL-8 interleukin 8, IL-15 interleukin 15, MCP-1 monocyte chemoattractant protein 1, RANTES regulated upon activation, normally T-expressed, and presumably secreted, also known as CC-motif chemokine ligand 5, THPO thrombopoieitin, VEGF-A vascular endothelial growth factor A.

ISSN: 1757-6512