1
|
PLAT
|
Plasminogen activator, tissue
|
4.52
|
247.12
|
54.67-fold ↑
|
Induces EC proliferation
|
2
|
PDGFRA
|
Platelet-derived growth factor receptor, alpha polypeptide
|
38
|
76
|
2-fold ↑
|
3
|
CAV1
|
Caveolin-1
|
6
|
2
|
3-fold ↓
|
Inhibits EC proliferation
|
4
|
COL18A1
|
Collagen, type XVIII, alpha 1
|
463
|
19
|
24-fold ↓
|
5
|
PROCR
|
Protein C receptor, endothelial
|
0.61
|
7.69
|
12.6-fold ↑
|
Induces EC survival
|
6
|
F2R
|
Protease-activated receptor-1
|
1.8
|
10.91
|
6.06-fold ↑
|
7
|
TGFB1
|
Transforming growth factor beta 1
|
0.96
|
37.26
|
138-fold ↑
|
8
|
BCL2L1
|
BCL2-like 1
|
1.4
|
140.43
|
100.3-fold ↑
|
9
|
MMP1
|
Matrix metallopeptidase 1
|
1.06
|
24
|
22.64-fold ↑
|
10
|
KDR
|
Vascular endothelial growth factor receptor 3 (VEGFR3)
|
0.62
|
50.83
|
81.92-fold ↑
|
11
|
SPHK1
|
Sphingosine kinase 1
|
1330.29
|
1,156,189.43
|
869.12-fold ↑
|
12
|
TNFSF10
|
TNF-related apoptosis-inducing ligand (TRAIL)
|
1.65
|
1788.25
|
1083-fold ↑
|
13
|
FASLG
|
Fas ligand
|
18,254.05
|
9.84
|
1855.08-fold ↓
|
Induces EC apoptosis
|
14
|
ENG
|
Endoglin
|
60.47
|
1.89
|
31.99-fold ↓
|
Induces EC injury
|
15
|
AGTR1
|
Angiotensin II receptor, type 1
|
2366.34
|
227.48
|
10.4-fold ↓
|
16
|
THBD
|
Thrombomodulin
|
131.78
|
10.19
|
12.93-fold ↓
|
17
|
IL3
|
Interleukin 3
|
47.75
|
0.59
|
80.93-fold ↓
|
Induces EC inflammation
|
18
|
ALOX5
|
Arachidonate 5-lipoxygenase
|
103.45
|
0.82
|
126.15-fold ↓
|
19
|
FLT1
|
Vascular endothelial growth factor receptor 1
|
7.14
|
1.96
|
3.64-fold ↓
|