Fig. 4

Functional response to cell transplantation or PBS injection in individual animals based on urethral profilometry. The left column shows the changes in maximal urethral pressure close (MUCP) and the right column shows the changes in the area under the profile curve (functional area - FA). “Before Tx/ini” values constitute the mean from UPP1 and UPP2 measurements in a certain animal. “After Tx/ini” values come from measurements at the terminal experimental point - either 28th day (1 m) or 84th day (3 m). Data before and after injection were analyzed using the non-parametric Wilcoxon test. In groups, where the statistically significant difference was noted the p value is presented. Tx, transplantation; ini, injection; MDC, muscle-derived cells; MSC, mesenchymal stem/stromal cells; MDC-MSC, MDCs and MSCs co-transplanted