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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Gene expression profiling of chondrogenic differentiation by dexamethasone-conjugated polyethyleneimine with SOX trio genes in stem cells

Fig. 7

Assessment of induction levels of chondrogenic differentiation of hMSCs cultured in a 3D system. a, b RT-PCR and Western blot analysis of SOX9, COLII, and COLI. c Glycosaminoglycan (GAG) assay hMSCs transfected with nothing (panel a), DEX/PEI only (panel b), trio-coated PEI (panel c), and DI-NPs (panel d). d Histological analysis of non-treated (panels a–c), Dexamethasone-conjugated polyethyleneimine (DEX/PEI)-treated (panels d–f), trio-coated PEI treated (panels g–i), and differentiation-inducing nanoparticle (DI-NP)-treated (panels j–l) hMSCs cultured in a 3D system. n = 5. **p < 0.01. COL collagen, H&E hematoxylin and eosin

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