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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Exosomes derived from miR-92a-3p-overexpressing human mesenchymal stem cells enhance chondrogenesis and suppress cartilage degradation via targeting WNT5A

Fig. 2

Effects of miR-92a-3p-MSC-Exos on migration and proliferation in chondrocytes. a–b Normalized gene expression levels in MSC-Exos and chondro-differentiated MSC-Exos detected by miRNA microarray. Three independent samples were used. c Gene expression levels of highly expressed genes in MSC-chondro-differentiated-Exo vs MSC-Exos and gene expression levels of miR-92a-3p. d MSC-Exos and miR-92a-3p-MSC-Exos were treated with chondrocytes at different doses. Quantitative data are presented as means ± standard deviations of three independent experiments. *P < 0.05. e Light microscopy images of scratch wound assays. f Quantitative analysis of migration rates at 24 and 48 h. Quantitative data are presented as means ± standard deviations of three independent experiments. **P < 0.01

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Stem Cell Research & Therapy

ISSN: 1757-6512