Clinical trial number | Study type | Phase | n | Disease type | Length of trial (months) | DSC type | Status | Observed changes | Reference |
---|---|---|---|---|---|---|---|---|---|
NCT03386877 | Periodontal regeneration using DPSCs | _ | 29 | Periodontal diseases | 15 (January 2016 to April 2017) | DPSCs | Completed | Not known | [136] |
NCT02523651 | Periodontal regeneration of chronic periodontal disease patients receiving stem cell injection therapy | I and II | 40 | Periodontal diseases | 24 (December 2014 to December 2016) | 1×106 DPSCs immediately after periodontal scaling and root planing | Unknown | Change from baseline alveolar bone volume | – |
NCT01814436 | Revitalization of immature permanent teeth with necrotic pulp using SHEDs | I | 80 | Permanent incisor avulsed by trauma | 58 (February 2013 to October 2017) | SHEDs | Active | Pulp and apical regenerated | – |
NCT02464202 | Use of CBCT-based tooth replica in tooth autotransplantation to improve the outcome of tooth replacement in children | _ | 100 | Increase success rate of tooth transplantation | 56 (February 2013 to October 2017) | PDLSCs | Active | Not known | – |
NCT02731586 | Effect on allogenic MSCs on osseointegration of dental implants | Early phase I | 10 | Edentulous alveolar ridge | 27 (January 2016 to March 2018) | Dental pulp-derived allogenic MSCs | Active | Not known | – |
NCT02449005 | Autologous ABMSCs for the reconstruction of infrabony periodontal defects (PerioRegen) | I and II | 30 | Chronic periodontitis | 45 (January 2014 to September 2017) | ABMSCs | Active | Gain in clinical attachment level | – |
NCT03137979 | GMSC treatment of chronic periodontitis | I and II | 30 | Periodontitis | 36 (January 2017 to December 2019) | GMSCs, collagen scaffolds, and open flap debridement | Active | An increase in the height of alveolar bone in mm | – |
NCT01357785 | Periodontal tissue regeneration using autologous PDLSCs | I | 35 | Periodontal pocket | 32 (April 2011 to December 2014) | Autologous PDLSCs | Unknown | Increase in alveolar bone height and gain in clinical attachment level | [137] |
NCT01082822 | PDLSC implantation in the treatment of periodontitis | I and II | 80 | Chronic periodontitis | 24 (January 2010 to January 201)2 | PDLSC implantation (fabricated cell sheet pellets and cell sheet fragment) | Unknown | Not known | – |