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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Short-term physiological hypoxia potentiates the therapeutic function of mesenchymal stem cells

Fig. 4

Secretion profile of MSCs under long-term and short-term hypoxia. (a) In long-term culture, IL-8 levels were suppressed under hypoxia in both human and porcine MSCs. (b) In short-term culture, IL-8 was similarly suppressed under hypoxia in both human and porcine MSCs (p < 0.06). In pMSCs, significantly higher levels of the anti-inflammatories, GM-CSF (p < 0.05) and IL-1ra (p < 0.01) were secreted under hypoxia, as compared to normoxia

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