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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Human cardiac stem cells inhibit lymphocyte proliferation through paracrine mechanisms that correlate with indoleamine 2,3-dioxygenase induction and activity

Fig. 1

Schematic representation of immunomodulatory assay experiments. Carboxyfluorescein succinimidyl ester (CFSE)-labeled and phytohemagglutinin (PHA)-activated human peripheral blood mononuclear cells (hPBMCs) were cultured with mitomycin-treated human cardiac/stem progenitor cells (hCSCs)/human adipose-derived mesenchymal stem cell (hASCs) either in direct contact (DC), in a transwell support (TW), or in contact with mitomycin-C-treated hCSC/hASC conditioned medium (Cond.M.). Viable T lymphocyte proliferation was accessed by CFSE labeling of the CD3+ 7AAD– hPBMC population

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Stem Cell Research & Therapy

ISSN: 1757-6512