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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Human tissue-specific MSCs demonstrate differential mitochondria transfer abilities that may determine their regenerative abilities

Fig. 1

Human mesenchymal stem cells (MSCs) can transfer mitochondria to U87-MG cells and rat cardiomyocytes. (a) Representative confocal images of mitochondrial transfer from bone marrow–MSCs (labeled with MitoTracker® Green) to U87-MG cells and (b) rat cardiomyocytes (labeled with Cell Trace Violet shown in red and violet, respectively). Scale bar = 20 μm. (c) A representative flow cytometric data plot shows the percentage of recipient U87-MG cells that take up mitochondria from BM-MSCs. The first plot shows cells stained with only mitotracker labeled MSC cells in Q1 quadrant, second plot shows only cell trace labeled recipient U87-MG cells in Q3 quadrant and third plot shows double positive U87-MG cells in Q2 quadrant

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Stem Cell Research & Therapy

ISSN: 1757-6512