Fig. 5

MDS-MSCs and AML-MSCs induce Tregs similar to HD-MSCs. Graph represents percentage of CD4⁺/CD25⁺/FoxP3⁺ cells analyzed by flow cytometry with respect to percentage of CD4⁺ cells. Tregs induced by PBMCs alone used as control (mean ± SEM of four independent experiments). *P < 0.05 vs PBMCs alone. Differences not significant between MSC groups. PBMC peripheral blood mononuclear cell, HD-MSC mesenchymal stromal cell from healthy donor, MDS-MSC mesenchymal stromal cell from myelodysplastic syndrome patient, AML-MSC mesenchymal stromal cell from acute myeloid leukemia patient