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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Schwann cell-like differentiated adipose stem cells promote neurite outgrowth via secreted exosomes and RNA transfer

Fig. 4

Exosomes enhance neurite outgrowth. a NG108–15 neurons treated with exosomes isolated from undifferentiated ADSCs (+ uADSCs exos), Schwann cell-like differentiated stem cells (+ dADSCs exos), dedifferentiated dADSCs (+ de-dADSCs exos) or Schwann cells (+SCs exos) stained with βIII-tubulin antibody (green). Control NG108–15 neurons treated with DMEM only. Scale bar is 100 μm. b Quantification of neurite length mediated by dADSCs exosomes, de-dADSCs and Schwann cells (+SCs exos), mean ± SEM, ***P < 0.001 significantly longer neurites compared with control cultures. n.s is not significantly different

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Stem Cell Research & Therapy

ISSN: 1757-6512