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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Schwann cell-like differentiated adipose stem cells promote neurite outgrowth via secreted exosomes and RNA transfer

Fig. 5

Exosomes express mRNAs and miRNAs associated with neural regeneration. a and b qRT-PCR was used to measure Gap43, Tau, Rac1, RhoA levels in exosome preparations from Schwann cells, undifferentiated adipose stem cells (uADSCs) and Schwann cell-like differentiated adipose stem cells (dADSCs). Expression levels normalised to Schwann cell = 1. *P < 0.05 significant difference in expression levels between the groups shown by connecting lines. c qRT-PCR was used to measure miR-18a, miR-182, miR-21, miR-222, miR-1 levels in exosome preparations from Schwann cells, undifferentiated adipose stem cells (uADSCs) and Schwann cell-like differentiated adipose stem cells (dADSCs). Expression levels normalised to Schwann cell = 1. *P < 0.05 significant difference in expression levels between the groups shown by connecting lines

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