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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Human decidua basalis mesenchymal stem/stromal cells protect endothelial cell functions from oxidative stress induced by hydrogen peroxide and monocytes

Fig. 3

Proliferation of HUVEC measured by MTS. As compared to untreated HUVEC, the proliferation of HUVEC significantly increased in response to H2O2 alone or with different concentrations (1%, 5%, and 25%) of CMDBMSC in the presence of 100 μM H2O2 (a) and with different ratios of DBMSC to HUVEC (1:1, 1:5, and 1:10) in the presence of 100 μM H2O2 (b). As compared to HUVEC treated with H2O2 (HUVEC + H2O2), the proliferation of HUVEC significantly increased in response to different concentrations (1%, 5% and 25%) of CMDBMSC in presence of 100 μM H2O2 (a) and with different ratios of DBMSC to HUVEC (1:1, 1:5, and 1:10) in presence of 100 μM H2O2 (b). As compared to untreated HUVEC, HUVEC proliferation significantly increased in response to different concentrations (1%, 5%, and 25%) of CMDBMSC (a), and at a high ratio of DBMSC to HUVEC (1:1) (b). As compared to HUVEC cultured with CMDBMSC, HUVEC proliferation did not significantly change in response to H2O2 and CMDBMSCs, P > 0.05 (a). As compared to HUVEC cultured with low ratios of DBMSCs to HUVEC (1:5 and 1:10), HUVEC proliferation significantly increased in response to H2O2 and DBMSCs (b). *P < 0.05. Bars represent standard errors. Each experiment was performed in triplicate and repeated for five times with five independent preparations of DBMSCs and HUVEC

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