Table 6 DBMSCs effects on genes involved in endothelial cell (EC) biology. THUVEC (HUVEC were cultured with 100 μM H2O2 for 48 h). TDBMSC (HUVEC were cultured with DBMSC and 100 μM H2O2 for 48 h)
# | Gene symbol | Gene full name | THUVEC mean ΔΔ−2 values | TDBMSC mean ΔΔ−2 values | Fold change (TDBMSC Vs. THUVEC) P < 0.05 |
|---|---|---|---|---|---|
1 | ANGPT1 | Angiopoietin 1 | 1.35 | 0.64 | Fold change is not statically significant, P > 0.05 |
2 | AGTR1 | Angiotensin II Receptor Type 1 | 0.13 | 0.05 | |
3 | ALOX5 | Arachidonate 5-Lipoxygenase | 0.61 | 0.36 | |
4 | ANXA5 | Annexin A5 | 9 | 5 | |
5 | APOE | Apolipoprotein E | 0.01 | 0.01 | |
6 | BCL2L1 | BCL2L1 | 11 | 10 | |
7 | CALCA | Calcitonin Related Polypeptide Alpha | 0.71 | 0.70 | |
8 | CCL2 | C-C motif chemokine ligand 2 | 1 | 0.39 | |
9 | CX3CL1 | C-X3-C Motif Chemokine Ligand 1 | 0.50 | 0.34 | |
10 | EDN2 | Endothelin 2 | 0.01 | 0.01 | |
11 | FASLG | Fas Ligand | 0.39 | 2.54 | |
12 | FN1 | Fibronectin 1 | 0.06 | 0.04 | |
13 | ICAM1 | Intercellular Adhesion Molecule 1 | 1 | 0.30 | |
14 | IL3 | Interleukin 3 | 0.66 | 1.47 | |
15 | IL7 | Interleukin 7 | 0.10 | 2.81 | |
16 | KLK3 | Kallikrein Related Peptidase 3 | 1 | 2 | |
17 | MMP1 | Matrix Metallopeptidase 1 | 3 | 3 | |
18 | NOS3 | Nitric Oxide Synthase 3 | 1 | 0.92 | |
19 | NPPB | Natriuretic Peptide B | 0.80 | 0.32 | |
20 | OCLN | Occludin | 4.99 | 1.48 | |
21 | PDGFRA | Platelet Derived Growth Factor Receptor Alpha | 1.06 | 0.26 | |
22 | PGF | Placental Growth Factor | 1.40 | 2.96 | |
23 | PLAT | Plasminogen Activator, Tissue Type | 3.73 | 0.34 | |
24 | PLAU | Plasminogen Activator, Urokinase | 1.59 | 2 | |
25 | SELL | Selectin L | 0.16 | 0.09 | |
26 | SOD1 | Superoxide Dismutase 1 | 17 | 17 | |
27 | TGFB1 | Transforming Growth Factor Beta 1 | 9 | 7 | |
28 | ENG | Endoglin | 19 | 16 |