Fig. 2

MSCT improved SFRs in NOD mice, ameliorated lymphocytic infiltrations in submandibular glands, and regulated T cell responses. a Saliva flow rate of mice at day 28 after MSC/FLS/PBS treatment (n = 5 for each group). b Histopathology of submandibular glands determined by HE staining (n = 5 for each group). c–e Percentages and absolute numbers of Th17 (CD4+IL-17+), Tfh (CD4+CXCR5+PD-1+), and Treg (CD4+CD25+Foxp3+) cells in splenocytes of mice (n = 5 for each group). Data were analyzed by one-way ANOVA. Error bars denote ± SD. *p < 0.05, **p < 0.01, ***p < 0.001