Fig. 5

Two doses of MSCs led to immunosuppression in cervical lymph nodes, but not in mediastinal lymph nodes. a CD4⁺ T cells, b CD8⁺ T cells, and c CD4⁺CD25⁺Foxp3⁺ cell count in cLN; d CD4⁺ T cells, e CD8⁺ T cells, and f CD4⁺CD25⁺Foxp3⁺ cell count in mLN. CTRL control mice, E emphysema mice, SAL saline-treated mice, MSC MSC-treated group, MSCs mesenchymal stromal cells, cLN cervical lymph nodes, mLN mediastinal lymph nodes. The Kruskal–Wallis test followed by Dunn’s test was used for statistical comparison. Data are presented as median ± interquartile range. N = 10 animals/group. *Significantly different from CTRL (p < 0.05). ^#Significantly different from E-SAL (p < 0.05). ^‡Significantly different from E-MSC-1 dose (p < 0.05)