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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Impact of one versus two doses of mesenchymal stromal cells on lung and cardiovascular repair in experimental emphysema

Fig. 6

One or two doses of MSCs similarly decreased collagen fiber content, but two doses led to further elastogenesis. Collagen fiber content in airways and blood vessels and elastic fiber content on lung parenchyma. Arrows indicate elastic fibers (stained black). CTRL control mice, E emphysema mice, SAL saline-treated mice, MSC MSC-treated group, MSCs mesenchymal stromal cells. The Kruskal–Wallis test followed by Dunn’s test was used for statistical comparison. Data are presented as median ± interquartile range. N = 10 animals/group. *Significantly different from CTRL (p < 0.05). #Significantly different from E-SAL (p < 0.05). Significantly different from E-MSC-1 dose (p < 0.05)

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