Fig. 8

Two doses of MSCs, but not a one-dose regimen, led to improvement in cardiac function. a Diastolic right ventricle area and b PAT/PET ratio. CTRL control mice, E emphysema mice, SAL saline-treated mice, MSC MSC-treated group, MSCs mesenchymal stromal cells, PAT pulmonary artery acceleration time, PET pulmonary artery ejection time. One-way ANOVA followed by Tukey’s test was used for statistical comparison. Data are presented as means ± SD. N = 10 animals/group. *Significantly different from CTRL (p < 0.05). ^#Significantly different from E-SAL (p < 0.05). ^‡Significantly different from E-MSC-1 dose (p < 0.05)