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Table 1 Lung morphometry

From: Impact of one versus two doses of mesenchymal stromal cells on lung and cardiovascular repair in experimental emphysema

  Normal (%) Collapse (%) Hyperinflation (%) Lm (μm) Neutrophils (%) Mononuclear cells (%)
CTRL 91.7 ± 2.1 8.3 ± 2.1 0.0 ± 0.0 22.3 ± 5.1 1.6 ± 0.7 33.8 ± 2.3
E SAL 18.4 ± 4.9* 27.2 ± 8.6* 54.4 ± 9.9* 50.3 ± 6.7* 7.3 ± 0.8* 42.4 ± 3.6*
MSC 1 dose 41.5 ± 4.8*,# 15.9 ± 4.8*,# 42.6 ± 4.1*,# 33.4 ± 2.8*,# 2.9 ± 0.9*,# 31.6 ± 4.0#
2 doses 51.4 ± 11.3*,#,ǂ 17.9 ± 4.4*,# 30.7 ± 6.3*,#,ǂ 29.8 ± 4.2*,#,ǂ 1.7 ± 0.5#,ǂ 36.1 ± 3.3#
  1. Volume fraction of normal, collapsed, and hyperinflated pulmonary areas, mean linear intercept (Lm), and neutrophil and mononuclear cell counts in lung tissue. One-way ANOVA followed by Tukey’s test was used for statistical comparison. Data are presented as means ± SD. N = 10 animals/group
  2. CTRL control mice, E emphysema mice, SAL saline-treated mice, MSC MSC-treated mice
  3. *Significantly different from CTRL (p < 0.05)
  4. #Significantly different from E-SAL (p < 0.05)
  5. ǂSignificantly different from E-MSC-1 dose (p < 0.05)