Fig. 2From: Modeling hallmark pathology using motor neurons derived from the family and sporadic amyotrophic lateral sclerosis patient-specific iPS cellsNeuron differentiation of iPSCs. a Schematic protocol for MN and non-MN differentiation. 3c, 3 small molecular compounds; Pur, purmorphamine; Cyclo, cyclopamine. b Immunofluorescent images of OLIG2+ MN progenitors, MNX1+postmitotic MNs, CHAT+ maturing MNs, SOX2+ progenitors, MNX1− and CHAT− spinal non-MNs. c Quantification of TUJ+ neuronal population among total Hoechst-labeled (HO) cells and MNX1+ MNs among neurons. Scale bar = 50 μmBack to article page