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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Modeling hallmark pathology using motor neurons derived from the family and sporadic amyotrophic lateral sclerosis patient-specific iPS cells

Fig. 2

Neuron differentiation of iPSCs. a Schematic protocol for MN and non-MN differentiation. 3c, 3 small molecular compounds; Pur, purmorphamine; Cyclo, cyclopamine. b Immunofluorescent images of OLIG2+ MN progenitors, MNX1+postmitotic MNs, CHAT+ maturing MNs, SOX2+ progenitors, MNX1 and CHAT spinal non-MNs. c Quantification of TUJ+ neuronal population among total Hoechst-labeled (HO) cells and MNX1+ MNs among neurons. Scale bar = 50 μm

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