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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Long-term effectiveness of local BM-MSCs for skeletal muscle regeneration: a proof of concept obtained on a pig model of severe radiation burn

Fig. 7

Course of gene expression from blood monocytes differentiated in different culture conditions from pigs before irradiation (C), on the day of surgery (Irr), and 2, 3, 4, 6, and 12 months after flap surgery with or without BM-MSC treatment. Macrophages were generated from blood monocytes in the presence of M-CSF. Real-time-PCR a in an unstimulated condition, b in an M1 condition after stimulation with LPS and IFN-γ, and c in an M2a condition, after stimulation with IL-4. Data are expressed relative to control skeletal muscle and normalized to GAPDH

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Stem Cell Research & Therapy

ISSN: 1757-6512