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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Human UCB-MSCs treatment upon intraventricular hemorrhage contributes to attenuate hippocampal neuron loss and circuit damage through BDNF-CREB signaling

Fig. 6

hUCB-MSC treatment reinstates synaptic function through BDNF signaling. Learning and memory functional outcomes on passive avoidance test (a) and Y-maze (b) at P32. Data are expressed as mean ± standard error of the mean (SEM). *p < 0.05 versus normal, #p < 0.05 versus IVH control, Φp < 0.05 versus IVH+MSC, Ψp < 0.05 versus IVH+scrambled siRNA-transfected MSCs. c Schematic diagram of hUCB-MSC-induced BDNF signaling after IVH in rat hippocampus

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Stem Cell Research & Therapy

ISSN: 1757-6512